Genetics of Tuberculosis in Irish Dairy Cattle
نویسندگان
چکیده
There is a lack of information on genetic parameters for tuberculosis (TB) susceptibility in dairy cattle. Mycobacterium bovis is the primary agent of tuberculosis in cattle.The objective of this study was to quantify the genetic variation present among Irish Holstein Friesian dairy cattle in their susceptibility to M. bovis infection. A total of 15,182 cow and 8,104 heifer single intradermal comparative tuberculin test (a test for M. bovis-purified protein derivative [PPD] responsiveness) records from November 1, 2002, to October 31, 2005 were available for inclusion in the analysis. Data on abattoir TB carcass lesions (confirmed M. bovis infection) were also available for inclusion in the analysis. Linear animal models, and sire and animal threshold models were used to estimate the variance components for susceptibility to M. bovis-PPD responsiveness and confirmed M. bovis infection. Heritability estimates from the threshold sire models were biased upwards. The threshold
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An outbreak of tuberculosis affecting cattle and people on an Irish dairy farm, following the consumption of raw milk
UNLABELLED Bovine tuberculosis is an ongoing problem in Ireland, and herd incidence has remained at approximately 5% for some years. Spillover of infection from cattle to people remains an ever-present possibility, given the ongoing pool of infection in the Irish cattle population. This paper describes an outbreak of tuberculosis affecting cattle and people on a dairy farm in southeastern Irela...
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